Natsuko Chiba Selected Research

Squamous Cell Carcinoma (Epidermoid Carcinoma)

7/2018	Loss of protein phosphatase 6 in mouse keratinocytes enhances K-rasG12D -driven tumor promotion.
12/2006	Dose escalation study of docetaxel and nedaplatin in patients with relapsed or refractory squamous cell carcinoma of the esophagus pretreated using cisplatin, 5-fluorouracil, and radiation.

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Natsuko Chiba Research Topics

Disease

17	Neoplasms (Cancer) 03/2024 - 07/2004
6	Breast Neoplasms (Breast Cancer) 04/2024 - 02/2010
5	Ovarian Neoplasms (Ovarian Cancer) 01/2024 - 07/2004
2	Ovarian Epithelial Carcinoma 01/2024 - 01/2023
2	Colorectal Neoplasms (Colorectal Cancer) 04/2023 - 07/2005
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 07/2018 - 12/2006
2	Carcinogenesis 07/2018 - 09/2015
2	Papilloma (Papillomatosis) 07/2018 - 09/2015
2	Carcinoma (Carcinomatosis) 08/2007 - 07/2006
2	Neoplasm Metastasis (Metastasis) 07/2006 - 07/2005
1	Stomach Neoplasms (Stomach Cancer) 01/2022
1	Hypoxia (Hypoxemia) 01/2022
1	Genomic Instability 05/2020
1	Sarcoma (Soft Tissue Sarcoma) 01/2017
1	Esophageal Squamous Cell Carcinoma 09/2015
1	Cockayne Syndrome (Syndrome, Cockayne) 10/2011
1	Esophageal Neoplasms (Esophageal Cancer) 12/2006
1	Neutropenia 12/2006
1	Melanoma (Melanoma, Malignant) 07/2006
1	Barrett Esophagus (Barrett's Esophagus) 07/2005
1	Abdominal Pain (Pain, Abdominal) 07/2005
1	Adenocarcinoma 07/2005

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 04/2024 - 10/2011
5	DNA (Deoxyribonucleic Acid)IBA 01/2024 - 02/2010
4	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2024 - 11/2021
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2023 - 07/2005
2	Adenosine Triphosphatases (ATPase)IBA 04/2024 - 03/2024
2	olaparibIBA 01/2024 - 01/2024
2	PlatinumIBA 01/2022 - 11/2021
2	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 12/2006
2	protein phosphatase 6IBA 07/2018 - 09/2015
2	Docetaxel (Taxotere)FDA Link 01/2017 - 12/2006
2	Amino Acids FDA Link 03/2013 - 07/2004
2	BRCA1 ProteinIBA 03/2013 - 02/2010
2	Fluorouracil (Carac)FDA LinkGeneric 12/2006 - 07/2005
2	UbiquitinIBA 07/2005 - 07/2004
2	Ligases (Synthetase)IBA 07/2005 - 07/2004
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 04/2024
1	Estrogens (Estrogen)FDA Link 03/2024
1	Carrier Proteins (Binding Protein)IBA 03/2024
1	Therapeutic UsesIBA 01/2024
1	Bevacizumab (Avastin)FDA Link 01/2024
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2024
1	Cetuximab (Erbitux)FDA Link 04/2023
1	Glycogen Synthase (Synthase I)IBA 01/2022
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2022
1	Capecitabine (Xeloda)FDA Link 01/2022
1	CateninsIBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 11/2021
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 05/2020
1	Tamoxifen FDA LinkGeneric 07/2018
1	TubulinIBA 06/2018
1	Gemcitabine FDA Link 01/2017
1	Phenobarbital (Luminal)FDA Link 04/2016
1	Estrogen ReceptorsIBA 04/2016
1	Isoleucine (L-Isoleucine)FDA Link 09/2015
1	Phenylalanine (L-Phenylalanine)FDA Link 09/2015
1	CarcinogensIBA 09/2015
1	Codon (Codons)IBA 09/2015
1	AcetoneIBA 09/2010
1	nedaplatinIBA 12/2006
1	Leucovorin (Folinic Acid)FDA Link 07/2005
1	alpha-Fetoproteins (alpha-Fetoprotein)IBA 07/2005
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 07/2004

Therapy/Procedure

5	Therapeutics 01/2022 - 07/2005
4	Drug Therapy (Chemotherapy) 04/2023 - 07/2005
1	Euthanasia (Mercy Killing) 07/2018
1	Ligation 09/2015
1	Endoscopes 07/2006
1	Chemoradiotherapy 07/2006
1	Esophagectomy 07/2005